CoomassieÊProstainªÊis a formulation of colloidal Coomassie Brilliant Blue G-250 stain developed for staining proteins. It isÊready-to-use, fast, sensitive, and safe.ÊThis stain eliminates extensive solution preparation time and expenditure. Unlike traditional Coomassie¨ stains, Coomassie ProStainª does not require fixatives and destains containing organic solvents (methanol or ethanol) or acetic acid. Coomassie ProStainª is easy to use and the visualization process can be completed in less than 2 hours (Basic protocol) and 20 minutes (Heat-mediated protocol). Proteins stained using the Coomassie ProStainª are compatible with mass spectrometry (MS) analysis.