Nature's Way Hydraplenish Hyaluronic Acid with MSM contains the patented BioCell Collagen II complex for healthy connective tissue and synovial fluid – plus the nutritional support of OptiMSM®. Hydraplenish provides a lower molecular weight hyaluronic acid than other sources giving it superior bioavailability. BioCell® Collagen provides collagen – the most abundant protein found in the body along with chondroitin, hyaluronic acid, glucosamine and other proteoglycans essential for the hydration and health of all connective tissues. MSM is a natural sulphur compound with many benefits including connective tissue elasticity and strength plus inflammation and pain modulation.

Hyaluronic acid is a "gelatin-like" fluid that acts as a natural lubricant within the body. It's an important part of healthy connective tissue, and is also abundant in the eyes, joints, heart valves and skin. The BioCell Collagen complex (Hydrolized collagen Type II, chondroitin sulfate, hyaluronic acid) in Hydraplenish is derived from chicken sternum.