VEGFB (R125) Polyclonal Antibody

Catalogue Numbers: BS1490-50, BS1490-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P49765

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). VEGF is a dimeric glycoprotein with struc- tural homology to PDGF. Several variants of VEGF have been described that arise by alternative mRNA splicing. It has been speculated that VEGF may function as a tumor angiogenesis factor in vivo. Two additional proteins des- ignated VEGF-B and VEGF-C share a significant degree of homology withVEGF. VEGF-B is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: VEGFB (R125) polyclonal antibody detects endogenous levels of VEGFB protein.

Extra Notes: Western blot (WB) analysis of VEGFB (R125) polyclonal antibody at 1:500 dilution
Lane1:K562 whole cell lysate(40ug)
Lane2:A549 whole cell lysate(40ug)
Lane3:The Heart tissue lysate of Rat(40ug)
Lane4:The Heart tissue lysate of Mouse(40ug)

Bioworld Molecular Weight: ~ 22 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VEGFB; VRF

Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human VEGFB.

Conjugate: Unconjugated

Modification: Unmodified