Sar1B rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6499-50, ES6499-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010],

Alternate Name: SAR1B; SARA2; SARB; GTP-binding protein SAR1b; GTP-binding protein B; GTBPB

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human SAR1B. AA range:111-160

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 22kD

Human Gene ID: 51128

Human SWISS Prot NO: Q9Y6B6

Subcellular Location: Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus Golgi stack membrane; Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.

Research Use Only