4E-BP1 Monoclonal Antibody Size: 50μL, 100μL Catalogue Numbers: RA10704-50, RA10704-100 Citations, Manuals and MSDS Available upon request. Background: eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008], Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Storage Instructions: -20°C/1 year Applications: WB; IHC-p; IF (paraffin section) ; ELISA Species Cross-Reactivity: Human GeneID (Human): 1978 SWISS: Q13541 Source: Mouse Research Use Only