Thrombomodulin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10270-50, MB10270-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P07204

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 60 kDa; Observed MW: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Thrombomodulin in A549 using Thrombomodulin antibody, and DAPI., Western blot analysis of Thrombomodulin in Jurkat lysates using Thrombomodulin antibody.

Alternative Name: CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM

Immunogen: A synthetic peptide of human Thrombomodulin

Conjugate: Unconjugated

Modification: Unmodified