Amfenac Sodium Hydrate is a COX-2 inhibitor.

Product information

Molecular Weight: 300.30

Formula: C15H14NNaO4

Chemical Name: 2-{2-amino-3-[(2, 3, 4, 5, 6-H)benzoyl]phenyl}acetate hydrate sodium

Smiles: O.[Na+].[2H]C1=C(C(=O)C2=CC=CC(CC([O-])=O)=C2N)C([2H])=C([2H])C([2H])=C1[2H]

InChiKey: QZNJPJDUBTYMRS-MWOUIWNMSA-M

InChi: InChI=1S/C15H13NO3.Na.H2O/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10;;/h1-8H,9,16H2,(H,17,18);;1H2/q;+1;/p-1/i1D,2D,3D,5D,6D;;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Marshall JC, et al. The effects of a cyclooxygenase-2 (COX-2) expression and inhibition on human uveal melanoma cell proliferation and macrophage nitric oxide production. J Carcinog. 2007 Nov 27;6:17.
2. Matsumoto T, et al. Effect of a non-steroidal anti-inflammatory drug (amfenac sodium) on polymorphonuclear leukocytes. Pharmacol Res Commun. 1982 Jun;14(6):523-32.

Products are for research use only. Not for human use.